Differin Adapalene Gel 0.1% (15 g)

The over-the-counter retinoid our viewers ask about the most. Always follow the label, and be patient with it.

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The Pore Tube Fit Check

Our pick for: People who want to learn about a long-term, over-the-counter routine step

Skill level: Intermediate (read the label, start slow)

Where it fits: Nighttime, on clean dry skin

Our verdict: The question we get more than any other. Read the label, start slow, and talk to a dermatologist if you’re unsure.

This one lives in almost every comment section on skincare content: “have you tried Differin?” Adapalene 0.1% is an over-the-counter retinoid, and because it’s a drug product, it comes with real directions you should read and follow.

Why it earned a spot on our shelf

We include it because it’s genuinely the most-asked-about product in the category, and we’d rather point you to the real thing with the real label than leave you guessing. It’s a long-game product, not a quick fix, and it’s for people who are ready to be consistent.

How to get started

  1. Read the full Drug Facts label before your first use.
  2. Apply as directed on the label, at night, on clean dry skin.
  3. Use a thin layer. More is not better.
  4. Moisturize, and wear sunscreen every day while you use it.
  5. Give it time, and stop and check with a professional if your skin reacts badly.

Coach’s tip

Most people who quit early do too much too fast. Start slow and keep the rest of your routine gentle.

Pair it with

COSRX Snail Essence, Thayers Toner, Hero Mighty Patch

Skip it if…

you’re pregnant or trying to get pregnant, or already using another retinoid. Ask a doctor or pharmacist first.

Heads up: this is an Amazon affiliate link. As an Amazon Associate, Pore Tube earns from qualifying purchases, at no extra cost to you. It never changes what we recommend.